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For some important receptors, it is way more. For instance, the relevant mutations occur in 69 percent of people in the GLP1 receptor that is the target of diabetes medicine and in 86 percent of people in the CNR2 receptor that is used as a target for medicine to relieve nausea induced by chemotherapy. But of course, we cannot know every person"s genome and so these are estimates based on the data sets available", says Alexander Hauser. The researchers use their findings and sales data for the 279 GPCR-relevant drugs from the National Health Service in the UK to estimate how much money is spent on medicine with little or no effect.

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"Years ago, I don't think many people thought much about sharing a room with somebody. I don't think people want to share a room with somebody today. " "This might mean that the medicine simply works less efficiently.]